Ming-Tsan SuPersonal data of - School of Life Science-National Taiwan Normal University

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Name	Ming-Tsan Su
Office phone number	7734-6244
Fax	2931-2904
Office	C201
E-mail	mtsu@ntnu.edu.tw

Category	Cell Biology and Molecular Medicine
Job title	Associate Professor
Discipline	Molecular Biology,Developmental Biology,Genetics,Topics in Biotechnology
Research expertise	Molecular Biology,Developmental Biology

Journal paper summary
Year	Publication	Author
2011	Wang YC, Lee CM, Lee LC, Tung LC, Hsieh-Li HM, Lee-Chen GJ, Su MT,2011,Mitochondrial dysfunction and oxidative stress contribute to the pathogensis of SCA12.,J Biol Chem,286,pp21742-21754	Ming-Tsan Su
2010	Yeh PA, Chien JY, Chou CC, Huang YF, Tang CY, Wang HY, Su MT,2010, Drosophila notal bristle as a novel assessment tool for pathogenic study of Tau toxicity and screening of therapeutic compounds.,Biochem Biophys Res Commun,391,pp510-516	Ming-Tsan Su
2010	Yeh, P.A., Chang, C.J., Tu, P.H., Wilson, H.I., Chien, J.Y., Tang, C.Y. and Su MT.,2010,Phosphorylation alters tau distribution and elongates life span in Drosophila.,J Alzheimers Dis,21,pp543-556	Ming-Tsan Su
2010	Lin CH, Chen CM, Hou YT, Wu YR, Hsieh-Li HM, Su MT, Lee-Chen GJ,2010,The CAG repeat in SCA12 functions as a cis element to up-regulate PPP2R2B expression.,Hum Genet ,128,pp205-212	Ming-Tsan Su
2009	Lee LC, Chen CM, Chen FL, Lin PY, Hsiao YC, Wang PR, Su MT, Hsieh-Li HM, Hwang JC, Wu CH, Lee GC, Singh S, Lin Y, Hsieh SY, Lee-Chen GJ, Lin JY ,2009,Altered expression of HSPA5, HSPA8 and PARK7 in spinocerebellar ataxia type 17 identified by 2-dimensional fluorescence difference in gel electrophoresis.,Clinica Chimica Acta,400,pp56-62	Ming-Tsan Su
2009	Chen CM, Hou YT, Liu JY, Wu YR, Lin CH, Fung HC, Hsu WC, Hsu Y, Lee SH, Hsieh-Li HM, Su MT, Chen ST, Lane HY, Lee-Chen GJ ,2009,PPP2R2B CAG repeat length in the Han Chinese in Taiwan: association analyses in neurological and psychiatric disorders and potential functional implications.,Am J Med Genet B Neuropsychiatr Genet ,150,pp124-129	Ming-Tsan Su
2009	Chen IC, Lin HY, Lee GC, Kao SH, Chen CM, Wu YR, Hsieh-Li HM, Su MT, Lee-Chen GJ ,2009,Spinocerebellar ataxia type 8 larger triplet expansion induces compact chromatin and RNA foci.,BMC Mol Biol,10,pp9-	Ming-Tsan Su
2009	Lee, C.M., Su, MT. and Lee, H.J.,2009,Pigment dispersing factor: an output regulator of the circadian clock in the German cockroach.,Journal of biological rhythms,24,pp35-43	Ming-Tsan Su
2008	Chen, W. L., Lin, J. W., Huang, H. J., Wang, S. M., Su, MT., Lee-Chen, G. J., Chen, C. M. and Hsieh-Li, H. M.,2008,SCA8 mRNA expression suggests an antisense regulation of KLHL1 and correlates to SCA8 pathology.,Brain Res,1233,pp176-184	Ming-Tsan Su
2006	Liu, M., Su, M.T., Lyons, G.E., and Bodmer, R.,2006,Functional conservation of zinc finger-homeodomain gene zfh-1/SIP1 in Drosophila heart development.,Development Gene and Evolution,216,11,pp683-693 (OTHER)	Ming-Tsan Su
2005	Chen CM, Lane HY, Wu YR, Ro LS, Chen FL, Hung WL, Hou YT, Lin CY, Huang SY, Chen IC, Soong BW, Li ML, Hsieh-Li HM, Su MT, Lee-Chen GJ*,2005,Expanded trinucleotide repeats in the TBP/SCA17 gene, but not the KLHL1AS/SCA8 and PPP2R2B/SCA12 genes, are associated with schizophrenia.,Schizophr Res,78,pp131-136 (OTHER)	Ming-Tsan Su
2005	Chen CC, Liu YC, Wu CH, Yeh CC, Su MT and Wu YC.,2005,Preparation of Fluorescent Silica Nanotubes and their Application in Gene Delivery.,Advanced Materials,17,4,pp404-407 (OTHER)	Ming-Tsan Su
2004	Tung LC, Su MT, Lu KT, Lee-Chen GJ.,2004,Genetic testing in spinocerebellar ataxia in Taiwan : expansions of trinucleotide repeats in SCA8 and SCA17 are associated with typical Parkinson’s disease.,Clin Genet.,65,3,pp209-214 (OTHER)	Ming-Tsan Su
2003	Chang JH, Pan JP, Tai DY, Huang AC, Li PH, Ho HL, Hsieh HL, Chou SC, Lin WL, Lo E, Chang CY, Tseng J, Su MT, Lee-Chen GJ ,2003,Identification and characterization of LDL receptor gene mutations in hyperlipidemic Chinese.,J Lipid Res.,44,10,pp1850-1858 (OTHER)	Ming-Tsan Su
2002	Han, Z., Fujioka, M., Su, M.-T., Liu, M., Jaynes, J. B., and Bodmer, R.,,2002,Transcriptional Integration of competence modulated by mutual repression generates cell-Type specificity within the cardiogenic mesoderm.,Developmental Biology,252,pp225-240 (OTHER)	Ming-Tsan Su
2000	Lockwood, W. K., Liu, M., Su, M.-T., and Bodmer, R. ,2000,A genetic model cardiac pattern formation and cell fate determination. In Genetic Models In Cardiorespiratory Biology.,Lung Biology Series., (OTHER)	Ming-Tsan Su
2000	Han, Z., Fujioka, M., Jaynes, J" Deo, M., Su, M.-T., and Bodmer, R. ,2000,Integration of positional, tissue-context and lineage information at the transcriptional level: specification of a cardiac cell-type, (in preparation) , (OTHER)	Ming-Tsan Su
1999	Su, M.-T., Fujioka, M., Goto, T., and Bodmer, R.,,1999,The Drosophila homeobox genes zfh-1 and even-skipped are required for cardiac-specific differentiation of a numb-dependent lineage decision.,Development,126,pp3241-3251 (OTHER)	Ming-Tsan Su
1999	Su, M.-T., Venkatesh, T. V., Golden, K? Wu, X., and Bodmer, R.,1999,The pioneer gene, apontic, is required for morphogenesis and function of the Drosophila heart.,Mechanisms of Development,80,pp125-132 (OTHER)	Ming-Tsan Su
1999	Venkatesh, T. V., Holland, N., Holland, L, Su, M.-T., and Bodmer, R.,1999,Sequence and developmental expression of amphioxus AmphiNk2-1: insights into the evolutionary origin of the vertebrate thyroid gland and forebrain.,Genes Evol.,209,pp254-259 (OTHER)	Ming-Tsan Su
1999	Verschueren, K., Remade, J.E., Collart, C., Kraft, H., Baker, B.S., Tyizanowski, P., Nelles, L., Wuytens, G., Su, M.-T., Bodmer, R? Smith, J. C., Huyiebroeck, D.,1999,SIP1, a novel zinc finger-homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes.,Journal of Biological Chemistry,274,pp20489-20498 (OTHER)	Ming-Tsan Su
1998	Su, M.-T., Venkatesh, T. V., and Bodmer, R,1998,Large and small scale preparation of bacteriophage l lysate and DNA. ,Biotechniques,25,1,pp44-46 (OTHER)	Ming-Tsan Su
1998	Su, M.-T., Golden, K., and Bodmer, R.,1998,X-gal staining of Drosophila embryos compatible for antibody staining or in situ hybridization.,Biotechniques,24,6,pp918-922 (OTHER)	Ming-Tsan Su

School name	Country	Department	Degree	Starting date
University of Michigan	America	Molecular Biology & Developmental Biology	Ph.D	1991-09 ~ 1998-08
				1985-09 ~ 1987-06
				1981-09 ~ 1985-06

Service organization/unit	Job title	Department	Responsbilities	Starting date
				2003-08 ~
				2000-08 ~ 2003-07
				1998-09 ~ 2000-07

Year	Conference period	Publication	Author
2011	2011/05/22 2011/05/25	Yang SA, Su MT,2011,Excessive Dpp Signaling induces cardial apoptosis through dTAK1 and dJNK during late embryogenesis of Drosophila,1st Asia-Pacific Drosophila Research Conference ,Taipei, ROC,2011/05/22-2011/05/25	Ming-Tsan Su
2011	2011/05/22 2011/05/25	Wang YC, Lee CM, Lee LC, Tung LC, Hsieh-Li HM, Lee-Chen GJ, Su MT ,2011,Mitochondrial dysfunction and oxidative stress contribute to the pathogensis of SCA12,1st Asia-Pacific Drosophila Research Conference ,Taipei, ROC,2011/05/22-2011/05/25	Ming-Tsan Su
2011	2011/05/22 2011/05/25	Wang HY, Su MT ,2011,Dysfunction of TBP dependent transcription may contribute to the pathogenesis of tauopathy,1st Asia-Pacific Drosophila Research Conference ,Taipei, ROC,2011/05/22-2011/05/25	Ming-Tsan Su
2011	2011/05/22 2011/05/25	Hsu TC, Su MT,2011,SCA17 is resulted from gain of toxicity function of mutant TBP and loss of function of normal TBP,1st Asia-Pacific Drosophila Research Conference ,Taipei, ROC,2011/05/22-2011/05/25	Ming-Tsan Su
2011	2011/05/22 2011/05/25	Chue YC, Su MT,2011,Role of Tws, a B regulatory subunit of PP2A, in mitochondrial fragmentation and autophagic response,1st Asia-Pacific Drosophila Research Conference ,Taipei, ROC,2011/05/22-2011/05/25	Ming-Tsan Su
2011	2011/05/22 2011/05/25	Yong CS, Su MT,2011,To investigate if TATA box binding protein is a regulator of p53 dependent apoptosis in Drosophila,1st Asia-Pacific Drosophila Research Conference ,Taipei, ROC,2011/05/22-2011/05/25	Ming-Tsan Su
2011	2011/03/30 2011/04/01	Hsu, TC, Su MT,2011, SCA17 is resulted from gain of toxicity function of mutant TBP and loss of function of normal TBP,52nd Drosophila research conference,San Diego, USA,2011/03/30-2011/04/01	Ming-Tsan Su
2011	2011/03/30 2011/04/01	Wang HY, Su MT ,2011,Dysfunction of TBP dependent transcription may contribute to the pathogenesis of tauopath,52nd Drosophila research conference,San Diego, USA,2011/03/30-2011/04/01	Ming-Tsan Su
2011	2011/00/00 2011/00/00	Yeh PA, Chang CJ, Tu, PS, Wilson, H, Chieh, JY Tang CY, Su MT,2011,Phosphorylation alters Tau distribution and elongates life span in Drosophila,1st Asia-Pacific Drosophila Research Conference,Taipei, ROC,2011/00/00	Ming-Tsan Su
2010	2010/08/23 2010/08/28	Wang YC, Lee CM, Lee LC, Tung LC, Hsieh-Li HM, Lee-Chen GJ, Su MT ,2010,Mitochondrial dysfunction and oxidative stress contribute to the pathogensis of SCA12,Symposium on Life Science between National Taiwan Normal University and Beijing Normal University,Beijing, China.,2010/08/23-2010/08/28	Ming-Tsan Su
2010	2010/04/07 2010/04/11	Wang YC, Su MT,2010,Tws, a regulatory subunit of PP2A, acts independently of Pink1 to promote apoptosis through mitochondrial fragmentation and oxidative stress,51st Drosophila research conference,Washington, DC, USA,2010/04/07-2010/04/11	Ming-Tsan Su
2010	2010/04/07 2010/04/11	Hsu, TC, Su MT ,2010,Role of TATA-box Binding Protein (TBP) in PolyQ Mediated Neurodegenerative Diseases: Implication of Transcription Dysfunction,51st Drosophila research conference,Washington, DC, USA,2010/04/07-2010/04/11	Ming-Tsan Su
2009	2009/09/01 2009/09/01	Wang YC, Su MT,2009,PPP2R2B promotes apoptosos through mitochondrial fragmentation and oxidative stress: pathogenic implication and therapeutic intervention of SCA12,2009 神經退化疾病治療國際研討會暨第三展小腦共濟失調症論文壁報獎,台北市,2009/09/01	Ming-Tsan Su
2009	2009/07/11 2009/07/14	Hsu TC, Su MT,2009,Deactivation of TBP as a common pathogenic mechanism in polyglutamine induced neuropathies,4th ESN conference on advances in molecular mechanisms of neurological disorders,Leipzig, German,2009/07/11-2009/07/14	Ming-Tsan Su
2009	2009/07/06 2009/07/08	Wang YC, Lee CM, Lee LC, Tung LC, Hsieh-Li HM, Lee-Chen GJ, Su MT ,2009,Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of SCA12,Tokyo, Japan,2009/07/06-2009/07/08	Ming-Tsan Su
2009	2009/07/06 2009/07/08	Yang SA, Su MT ,2009,Excessive Dpp Signaling induces cardial apoptosis through dTAK1 and dJNK during late embryogenesis of Drosophila,The 9th Japanese Drosophila research conference,Tokyo, Japan,2009/07/06-2009/07/08	Ming-Tsan Su
2006	2006/12/02 2006/12/02	Shiau HC, Su MT,2006,Generation and pathogenic study of SCA8 Drosophila model,小腦萎縮症國際醫學院研討會暨第二屆SCA論文壁報獎,台北市,2006/12/02	Ming-Tsan Su
2006	2006/12/02 2006/12/02	Yeh PA, Su MT ,2006,Functional identification and Characteization of Twins, Drosophila homolog of human PP55B, implication of SCA12 pathogenesis,小腦萎縮症國際醫學院研討會暨第二屆SCA論文壁報獎,台北市,2006/12/02	Ming-Tsan Su
2006	2006/08/24 2006/08/28	Yeh PA, Su MT,2006, Dissecting the function of PPP2R2B in neurogenesis and its implication in neurodegenerative diseases,16th Biennial meeting of the international society for developmental neuroscience ,Banff, Canada,2006/08/24-2006/08/28	Ming-Tsan Su
2006	2006/03/18 2006/03/19	Lin DH, Hsu CF, Su MT, Wu CL ,2006,Cloning the muscle-specific promoter of zebrafish to establish a whole fish gene trasgenesis platform,第二十一屆生物醫學聯合學術年會,Taiwan,2006/03/18-2006/03/19	Ming-Tsan Su

School of Life Science-National Taiwan Normal University

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